早产儿血清维生素E浓度测定

目的　测定早产儿维生素E的二种异构体α 生育酚和γ 生育酚的血清浓度,探讨早产儿体内维 生素E的水平。方法　选取早产儿、正常足月儿各16例,采用库仑阵列电化学法检测血清中维生素E水平。结果 与正常足月儿对比,早产儿血清α 生育酚浓度(217±120ng/mLvs411±284ng/mL)和γ 生育酚浓度(889±460 ng/mLvs2177±1031ng/mL)明显降低,差异有显著性意义(均P<0.05)。结论　早产儿体内维生素E储藏量相 对较少,容易发生维生素E缺乏。早产儿出生后应及时补充维生素E。

Serum concentrations of vitamin E in premature infants

Objective To examine serum vitamin E levels in premature infants. Methods Serum concentrations of two isomers of vitamin E, α-tocopherol and γ-tocopherol, were measured by electrochemistry in 16 premature infants and 16 full-term infants. Results Compared with term infants, the serum concentrations of α-tocopherol and γ-tocopherol in premature infants were significantly lower (217±120 ng/mL vs 411±284 ng/mL and 889±460 ng/mL vs 2 177±1 031 ng/mL, respectively, both P<0.05).Conclusions Premature infants have a much lower serum vitamin E level. Vitamin E supplementation is thus essential soon after birth.