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嗜人T淋巴细胞病毒I型(HTLV-I)相关HAM/TSP病(附5例报告)
引用本文:郑璇,杨棉华,杜登青,庄伟端,陈显光,陈国敏,曾毅.嗜人T淋巴细胞病毒I型(HTLV-I)相关HAM/TSP病(附5例报告)[J].临床神经病学杂志,1996(6).
作者姓名:郑璇  杨棉华  杜登青  庄伟端  陈显光  陈国敏  曾毅
作者单位:汕头大学医学院第一附属医院神经科,汕头大学医学院微生物学教研室,中国预防医学科学院病毒学研究所
基金项目:广东省医药卫生科研基金
摘    要:本文报道应用间接免疫荧光法,从汕头地区97例神经系统疾病患者血清中,检测出嗜人T淋巴细胞病毒I型(HTLV-I)抗体阳性的HTLV-I相关HAM/TSP病患者5例,阳性率为5.15%。并对HTLV-I相关HAM/TSP病的临床特点、伴发疾病、病理及发病机制、治疗等进行了讨论,认为国内进一步开展对HTLV-I相关HAM/TSP病的检测和研究是非常必要的。

关 键 词:嗜人T淋巴细胞病毒I型  脊髓疾病  热带痉挛性瘫痪

HTLV I associated myelopathy/tropical spastic paraparesis:A report of 5 cases in Shantou.
Zheng Xuan,YangMianhua,Du Dengqing,et al..HTLV I associated myelopathy/tropical spastic paraparesis:A report of 5 cases in Shantou.[J].Journal of Clinical Neurology,1996(6).
Authors:Zheng Xuan  YangMianhua  Du Dengqing  
Institution:Zheng Xuan,YangMianhua,Du Dengqing,et al.First Affiliated Hospital of Shantou University Medical College,Shantou,515041.
Abstract:This paper reports 5 cases of HTLV 1 associated myelopathy/tropical spastic paraparesis in Shantou.Sera from patients with various neuralogical diseases were screened for antibody to HTLV 1 using an indirect immunofluorescent assay.5 out of 97 cases(5.15%) were positive for HTLV 1 antibody.The clinical features,concomitant diseases,pathological features,pathogenesis and treatment of HAM/TSP are discussed.The discovery of the cases of HAM/TSP in China is considered to be highly significant.
Keywords:HTLV  1  Myelopathy  Tropical spastic paraparesis  
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