108例新生儿败血症的临床治疗分析

目的对新生儿败血症进行早期诊断和治疗,减少并发症,降低死亡率。方法分析108例血培养阳性患儿的临床资料。结果新生儿败血症临床表现无特异性,且并发症多,死亡率高,血培养仍为确诊的主要手段,病原菌以葡萄球菌为主,占48.14%。其中表皮葡萄球菌18例(16.67%),金黄色葡萄球菌15例(13.89%),溶血性葡萄球菌8例(7.41%)。其次为大肠杆菌和克雷伯氏菌分别为14.81%和9.26%。目前病原菌普遍敏感的抗生素为头孢唑啉、头孢哌酮、丁胺卡那霉素、万古霉素、环丙沙星。结论根据症状体征和药敏结果,早期应用敏感抗生素控制感染,积极防治并发症,可降低死亡率。

Clinical analysis on treatment of 108 neonates with septicemia

Objective:By early diagnosis and treatment of neonatal septicemia to reduce complications and mortality.Methods:The clinical data of 108 cases of neonatal septicemia with positive blood culture were analyzed.Results:Neonatal septicemia had various complications with high mortality, but no specific clinical manifestation.Blood culture was still the key means of diagnosis, the main pathogen was staphylococcus (48.14%), including 18 cases of staphylococcus epidermidis (16.67%), 15 staphylococcus aureus (13.89%), 8 staphylococcus hemolyticus (7.41%), The other pathogens included Escherichia coli (14.81%) and klebsiella (9.26%).The antibiotics all of the pathogenic bacteria with high sensitivity included cefazolin sodium, cefoperazone, amikacin sulfate, vancomycin, and ciprofloxacin.Conclusion:According to clinical manifestations and drug sensitivity, the sensitive antibiotics should be given early to prevent and treat complications and reduce mortality.