| 徐长卿中多糖CPB-4的化学结构研究 |
| |
| 引用本文： | 王顺春,鲍幸峰,方积年.徐长卿中多糖CPB-4的化学结构研究[J].中国中药杂志,2002,27(2):128-130. |
| |
| 作者姓名： | 王顺春 鲍幸峰 方积年 |
| |
| 作者单位： | 中国科学院,上海生命科学研究院,上海药物研究所,上海,200031 |
| |
| 摘 要： | 目的 :研究徐长卿中多糖CPB-4的化学结构。方法 :采用糖组成分析 ,甲基化分析 ,部分酸水解和13CNMR光谱等方法测定CPB 4的糖组成 ,连接方式 ,主链和支链结构及分枝点状况。结果 :CPB-4由L-阿拉伯糖 ,L-木糖 ,L-鼠李糖和D-半乳糖 =0.8∶0.2∶0.2∶1.0组成 ,主链由 1,5连接的半乳呋喃聚糖组成 ;侧链分枝主要位于半乳糖的6位 ,另有少量分枝位于半乳糖的2位 ;分枝的组成包括木糖端基、阿拉伯寡糖及由阿拉伯糖、鼠李糖和半乳糖组成的寡糖链。结论 :CPB-4为一新颖的中性杂多糖。
|
| 关 键 词： | 徐长卿 中性杂多糖 化学结构 |
| 文章编号： | 1001-5302(2002)02-0128-03 |
| 收稿时间： | 3/5/2001 12:00:00 AM |
| 修稿时间： | 2001年3月5日 |
Structural Features of a Neutral Heteropolysaccharide CPB-4 from Cynanchum paniculatum |
| |
| WANG Shun chun;BAO Xing feng;FANG Ji nian.Structural Features of a Neutral Heteropolysaccharide CPB-4 from Cynanchum paniculatum[J].China Journal of Chinese Materia Medica,2002,27(2):128-130. |
| |
| Authors: | WANG Shun chun;BAO Xing feng;FANG Ji nian |
| |
| Institution: | Shanghai Institute of Materia Medica, Shanghai Institute for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China. |
| |
| Abstract: | OBJECTIVE: To study the chemical features of CPB-4, a heteropolysaccharide obtained from Cynanchum paniculatum. METHOD: Sugar composition analysis, methylation analysis, partial hydrolysis and carbon-13 nuclear magnetic resonance were used to determine the sugar composition, linkages, main chain, branch chains and branching points. RESULT: CPB-4 is composed of L-arabinose, L-xylose, L-rhamnose and D-galactose in closely molar ratios of 0.8:0.2:0.2:1.0. Its main chain is comprised of 1, 5 linked galactose and side chains are comprised of terminal xylose, terminal arabinose, oligosaccharide of arabinose and oligosaccharide of arabinose, rhamnose and galactose. The branching points are located at C-6 and C-2 of galactose. CONCLUSION: CPB-4 is a new heteropolysaccharide from C. paniculatum. |
| |
| Keywords: | Cynanchum paniculatum neutral heteropolysaccharide chemical structure |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
