彩超对胎儿期卵圆孔闭合的诊断价值

目的：应用彩色多普勒超声观察胎儿心脏，观测胎儿时期卵圆孔的各项测量指标以预测其产后情况，并明确产后的重点随访对象，提高胎儿或新生儿继发孔型房缺的早期诊断。方法：选取胎儿期心脏结构、功能基本正常的病例，根据其产后房间隔闭合时间分为〈3个月闭合组、3～6个月闭合组、〉6个月尚未闭合等3组，比较各组产前的卵圆孔直径、卵圆孔流速、动脉导管流速、肺动脉内径、肺动脉流速。结果：随着房间隔闭合时间的延迟，胎儿时期的卵圆孔直径、动脉导管流速、肺动脉内径、肺动脉流速有增大趋势，卵圆孔流速有减慢趋势，对在6个月内闭合与未闭合的病例比较其差异，有统计学意义。结论：卵圆孔是胎儿心脏的重要血流通道．通过彩超对以上各项参数进行监测．能够对产后卵圆孔闭合的情况进行初步估测，从而对继发孔型房缺作出早期诊断。

Value of Color Doppler Ultrasound for Diagnosis of Foramen Ovale Closure in Fetal

Objective To observe the measurement indexes of fetal foramen ovale with color Doppler uhrasonography in order to predict its postpartum development, and to perform postpartum follow-up in order to promote the early diagnosis of secundum atrial septal defect of fetus and newborn. Mothods Some cases without fetal heart abnormality were divided into three groups respectively with the atrial septum closed within 3 months after delivery, beyond 3 months and within 6 months, or beyond 6 months. The indexes before delivery were compared including foramen ovale diameter, foramen ovale velocity, arterial duct velocity, pulmonary artery internal diameter as well as pulmonary artery velocity. Results All the above indexes except foramen ovale velocity increased with the atrial septum closure time. There was significant difference between the newborns with the atrial septum closed within 6 months and beyond 6 months. Conclusion Initial prediction for the foramen ovale closure after delivery can be realized by monitoring the above indexes with Color Doppler uhrasonography, and thus the early diagnosis of the secondary secundum atrial septal defect can be carried out.