| 麻黄碱衍生物对小鼠学习记忆的影响 |
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| 引用本文： | 常福厚 刘素珍 等. 麻黄碱衍生物对小鼠学习记忆的影响[J]. 内蒙古医学院学报, 2000, 22(4): 252-255 |
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| 作者姓名： | 常福厚 刘素珍 等 |
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| 作者单位： | [1]内蒙古医学院药学系药理室，010059 [2]呼和浩特市回民医院，010030 |
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| 摘 要： | 目的：研究麻黄碱衍生物（ephedrine derivatives,EDs）对正常小白 鼠学习记忆的影响及对小白鼠记忆获得、巩固、再现障碍的改善作用。方法：采用水迷宫法。结果：EDs对正常小白鼠有促进记忆的作用，并可以显著地改善东莨菪碱所致的记忆获得障碍，亚硝酸钠所致的记忆巩固障碍及乙醇所致的记忆再现障碍。结论：EDs改善小鼠的学习记忆功能。
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| 关 键 词： | 麻黄碱 记忆障碍 记忆 药理 |
EFFECTS OF EPHEDRINE DERIVATIVES ON DYSMNESIA OF MICE |
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| CHANG Fu-hou,LIU Su-zhen,XIN Zhong,WANG Cheng. EFFECTS OF EPHEDRINE DERIVATIVES ON DYSMNESIA OF MICE[J]. Acta Academiae Medicinae Neimongol, 2000, 22(4): 252-255 |
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| Authors: | CHANG Fu-hou LIU Su-zhen XIN Zhong WANG Cheng |
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| Abstract: | Objective:To explore the effects of ephedrine derivatives on acquired, consolidated and reappeared disturbance of memory of mice. Methods:The methods of water-maze were used. Results:Ephedrine derivatives can improve the acquired disturbance of memory caused by scopolamine,the consolidated disturbance of memory caused by sodium nitrite and reappeared disturbance of memory caused by ethyl alcohol remarkably. Conclusion:Ephedrine derivatives can improve the dysmnesia of mice. |
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| Keywords: | ephedrine dysmnesia memory |
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