冬菊洗液结合创面浸浴疗法治疗四肢深Ⅱ度烧伤临床研究

目的:观察冬菊洗液结合创面浸浴疗法治疗四肢深Ⅱ度烧伤的临床疗效。方法:将180例四肢深Ⅱ度烧伤患者按照随机数字法分为对照组和试验组,每组90例。对照组采用生理盐水局部浸浴后常规换药处理,试验组患者冬菊洗液局部浸浴后按常规换药处理。用药14 d后观察两组患者的创面治愈率和不良反应,并于用药前及治疗后7 d、14 d,培养、分离与鉴定细菌,并计算创面细菌清除率。结果:治疗后对照组创面治愈率为62.22%,试验组创面治愈率为86.67%,两组比较,差异有统计学意义(χ~2=7.067,P0.05);用药后两组患者均未见明显不良反应;用药前及用药后7d、14 d,两组患者均检出金黄色葡萄球菌、鲍氏不动杆菌、铜绿假单胞菌、大肠埃希菌等。试验组患者用药后7 d细菌清除率为50.0%,明显高出对照组20.0%,差异有统计学意义(χ~2=8.067,P0.01)。试验组患者用药后14 d细菌清除率为71.4%,明显高出对照组45.0%,差异有统计学意义(χ~2=5.896,P0.05)。结论:冬菊洗液结合创面浸浴疗法治疗四肢深II度烧伤能有效控制创面感染,显著提高治愈率。

Effectiveness of Balneotherapy with Dong-ju Lotion in Treating for Extremity Deep Second Degree Burn Wound

Objective To observe the effect of balneotherapy with dong-ju lotion in treating extremity deep second degree burn wound.Methods A total of 180 cases of extremity deep second degree burn wound between January 2011 and September 2015 were randomly divided into the treatment group (90 cases) and the control group (90cases).In the treatment group,the patients had a bath with dong-ju lotion,and then the wounds were treated with dressing change in routine method.In the control group,the patients had a bath with normal saline,and then the wounds were treated with dressing change in routine method.The healing condition,the adverse reaction and bacteria clearance were observed in two groups after treatment.Results The wound healing quality in treatment group was better than that in the other group.The bacterial clearance rate of the two groups was significantly different.No any adverse reactions in the treatment.Conclusion Balneotherapy with dong-ju lotion deep second degree burn wound in extremities is safe and efficient,It reduces the risks of the infection of wound and improve the healing quality.