医院PET-CT中心18F正电子放射性药物生产及使用中工作人员的辐射剂量监测

目的 研究以18F-脱氧葡萄糖（18F-FDG）为代表的正电子放射性药物在生产和使用过程中医务人员的辐射剂量，为临床辐射防护提供参考数据。方法 测量18例工作人员在制药、质控、分装、传送、注射及摆位的工作流程中手、胸部的当量剂量率（d）及操作时间（t），并结合不同年检查工作量（w）估算各工作场所工作人员的年受照剂量。结果 估算得到年检查工作量为1000、4000、7000和10000例时，不同工作环节工作人员的累计年剂量为质控0.27mSv，分装0.02～0.20mSv，传送0.06～0.58mSv，注射2.49～24.9 mSv，摆位1.19～11.91mSv。结论 在现有防护设施和操作条件下, 分装和注射是接受剂量较高的工作环节。当年检查工作量在4000例以上时，从事分装工作的人员手部受照剂量超过国家标准关于职业个人年剂量限值的规定；当年检查工作量在10000例时，从事注射的人员年有效剂量亦超过相关国家标准的规定。

Measurement and evaluation of personal radiation dose in cyclotron center and PET-CT department

Objective To measure and evaluate the personal radiation dose for medical staff in cyclotron center and PET-CT department and to offer the reference data for clinical radiation protection. Methods γ ray radiation dose rate was analyzed in 18 medical staff members during each medical procedure by using X and γ radiation detector. The estimation of annual exposure dose of 18 medical staff at different working site was based on the caculation of doserate(d), work time(t) and workload(w). Results When the workloads were 1000, 4000, 7000 and 10000 per year, the annual doses per procedure were: 0.27 mSv for quality control; 0.02 to 0.20 mSv for dispensation; 0.06 to 0.58 mSv for carrying the compound; 2.49 to 24.9 mSv for injection and 1.19 to 11.91 mSv for setting the patients. Conclusion The staff receives higher radiation dose during dispensation and injection. When the workload is 4000 and 10000 per year, the dose received by hands and body would respectively exceed the national radiation safety standards (GBSS) on occupational annual dose limits.