喘可治注射液治疗成人夜尿症30例临床观察

目的：观察喘可治注射液治疗成人夜尿症的临床疗效。方法：经辨证属于肾阳（气）虚的30例夜尿症患者，采用喘可治注射液肌肉注射，每次6mL，每天1次，疗程1月。于治疗1、2、3、4周对患者治疗前后的夜尿次数和无干扰睡眠时间变化进行评价。结果：所有的患者经过喘可治注射液治疗后，夜尿的次数均明显减少。夜尿次数从治疗前的（4．8±2．7）次显著减少到治疗1周的（2．4±1．9）次（P〈0．01）以及治疗结束的（1．5±1．4）次（P〈0．01）；同时治疗后无干扰睡眠时间也相应延长，从治疗前的（76．8±5．7）min显著延长到治疗1周的（159．5±21．3）man（P〈0．01）以及治疗结束的（239．8±25．6）min（P〈0．01）。结论：喘可治注射液治疗肾阳（气）虚的成人夜尿症患者疗效确定。

Therapeutic Effect of Chuankezhi Injection for Adult Nocturia:An Observation of 30 Cases

Objective： To observe the efficacy of Chuankezhi Injection in the treatment of adult nocturia. Methods： Thirty adult nocturia patients differentiated as kidney Yang or qi deficiency were intramuscularly injected with 6 mL of Chuankezhi Injection（6 mL, qd） for one month. Changes in daily nocturia frequency and sleeping time without interruption were recorded and evaluated weekly. Results： Improvements of daily nocturia frequency and sleeping time without interruption were observed only one week after treatment with Chuankezhi Injection, and the improvements became more obvious in later observation period. Daily nocturia frequency was markedly decreased from （4.8 ± 2.7） times（before treatment） to （2.4 ＋ 1.9） times （one week after treatment, P 〈 0.01） and （1.5 ± 1.4） times（at the end of treatment, P 〈 0.01）, while the sleeping time without interruption was significantly increased from （76.8 ± 5.7） min（before treatment） to （159.5 ± 21.3）min（one week after treatment, P 〈 0.01） and（239.8 ± 25.6）min（at the end of treatment, P 〈 0.01）. Conclusion： Chuankezhi Injection shows certain efficacy in the treatment of nocturia with deficiency of kidney Yang or qi.