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| 甘肃黄芩抗氧化有效成分的分离鉴定 | |
| 引用本文： | 苏亚伦,黄聿,陈振宇. 甘肃黄芩抗氧化有效成分的分离鉴定[J]. 中国中药杂志, 2004, 29(9): 863-864 |
| 作者姓名： | 苏亚伦 黄聿 陈振宇 |
| 作者单位： | 1. 中国医学科学院,药物研究所,北京,100050 2. 香港中文大学,生理系,香港 3. 香港中文大学,生物化学系,香港 |
| 摘 要： | 目的 :分离鉴定甘肃黄芩丙酮提取物的抗氧化有效成分。方法 :采用色谱柱进行分离 ,以波谱及标准品方法鉴定化合物的结构。结果 :从丙酮提取物中分离得到了5个化学成分 ,分别为千层纸素A(oroxylinA ,Ⅰ )、汉黄芩素 (wogonin ,Ⅱ )、黄芩素 (baicalein ,Ⅲ )、甘黄芩苷元 (ganhuangenin ,Ⅳ )、甘黄芩素 (ganhuangemin ,Ⅴ )。从甲醇提取物得到黄芩苷 (baicalin ,Ⅵ )。结论 :甘黄芩素 (ganhuangemin)为首次从甘肃黄芩中分离得到的二氢黄酮醇类化合物 ,黄芩素和甘黄芩苷元有较强的抗氧化活性 ,明显的高于BHT(butylatedhydroxytoluene)的抗氧化活性。 |
| 关 键 词： | 甘肃黄芩 甘黄芩素 甘黄芩苷元 黄芩素 抗氧化成分 |
| 文章编号： | 1101-5302(2004)09-0863-02 |
| 收稿时间： | 2004-04-06 |
Isolation and elucidation of antioxidant constituents from acet one extract in root of Scutellaria rehderiana |
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| SU Ya-lun ;HUANG Yu ;CHEN Zhen-yu. Isolation and elucidation of antioxidant constituents from acet one extract in root of Scutellaria rehderiana[J]. China Journal of Chinese Materia Medica, 2004, 29(9): 863-864 | |
| Authors: | SU Ya-lun HUANG Yu CHEN Zhen-yu |
| Affiliation: | Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China. suyalun@imm.ac.cn |
| Abstract: | Objective: To isolatate and elucidate the an tioxidant constituents from acetone extract of Scutellaria rehderiana. Method: Chemical constituents were isolated by several column c hromatographies and their structures were elucidated on the basis of standard co mpounds and spectral analysis. Result: Five compounds, oro xylin A, wogonin, baicalein, ganhuangenin, ganhuangemin were isolated from aceto ne extract of S. rehderiana. Baicalin was obtained from methanol extract of S. rehderiana. Conclusion: Ganhuangemin was isolated f rom the plant for the first time. Baicalein and ganhuangenin have stronger antio xidant activity than that of BHT (butylated hydroxytoluene). |
| Keywords: | Scutellaria rehderiana ganhuangenin g anhuangemin baicalein antioxidant constituents |
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