| 异位神经元与难治性癫痫间关系的临床研究 |
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| 作者姓名： | Yu T Wang Y Zhang G Li Y |
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| 作者单位： | 1. 100053,北京,首都医科大学宣武医院,北京功能神经外科研究所
2. 100053,北京,首都医科大学宣武医院,神经内科 |
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| 摘 要： | 目的 讨论异位神经元与难治性癫痫的关系。方法 通过MRI,视频脑电图和长程颅内电极记录以及皮层电极术中监测,精确定位致痫灶后行手术切除。送病理检查。结果 在7例患者送检的脑组织白质内发现异位神经元。而无其他特异性改变,术后癫痫发作消失。结论 白质内散在或灶状分布的异位神经元与难治性癫痫有关。
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| 关 键 词： | 难治性癫痫 异位神经元 相关性 脑白质 |
| 修稿时间： | 2002年5月30日 |
Relationship between the heterotopic neurons and intractable epilepsy |
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| Yu T,Wang Y,Zhang G,Li Y.Relationship between the heterotopic neurons and intractable epilepsy[J].Chinese Journal of Internal Medicine,2002,41(12):829-831. |
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| Authors: | Yu Tao Wang Yuping Zhang Guojun Li Yongjie |
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| Institution: | Department of Functional Neurosurgy, Xuanwu Hospital, The Capital University of Medical Science. Beijing 100053, China. lengyun318@163.net |
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| Abstract: | Objective To discuss the relationship between heterotopic neurons and intractable epilepsy Methods Epileptogenic zones were precisely located with MRI,video EEG monitoring,intracranial electrical recording and electrocorticography monitoring and then resected in seven patients The removed tissue was processed for conventional pathological examination with immunohistochemical staining Results Heterotopic neurons were found in the white matter of the specimens All the seven cases experienced a favorable outcome, with six seizure free Conclusion The heterotopic neurons scattered or clustered in the white matter contribute to the pathogenesis of intractable epilepsy |
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| Keywords: | Epilepsy complex partial Heterotopic neurons |
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