不同性别的老年髋部骨折愈合期骨代谢标志物的变化

目的：了解老年髋部骨折愈合期男、女性骨代谢标志物的变化,建立其自身的变化特征。方法对四川省骨科医院近两年收治的老年髋部骨折患者,在骨折初、愈合期第1、2、3、4、7周时测定其β胶原特殊序列（β‐CTX）、骨钙素片段中断（N‐MID）。结果老年髋部骨折患者β‐CTX均呈增加趋势,但男性增加晚于女性,且在第7周时较之前有下降。N‐MID在第7周时均明显增加,但男性在第1周时下降,第2周开始逐渐增加,女性在第1周时即增加,而在第2周时降低,以后又逐渐增加。结论老年髋部骨折患者骨折愈合期骨代谢标志物的变化因男女性别不同而有各自的特点。

Changes in bone metabolism markers during healing period in different genders of elderly hip fracture

Objective To understand the changes of bone metabolism markers in men and women during heal‐ing period of elderly hip fracture for establishing their own change characteristics .Methods β‐CTX and N‐MID were detected at the early fracture ,1 ,2 ,3 ,4 ,7 weeks of fracture healing in the elderly patients with hip fractures admitted in our hospital in the last two years .Results β‐CTX showed a increasing trend in elderly patients with hip fracture , but the increase in males was later than that in females ,and which at 7 weeks was decreased than before .N‐MID at 7 weeks was significantly increased ,which in the males was decreased at 1 week and gradually increased at 2 weeks , while which in females was increased at 1 week and decreased at 2 weeks ,but later gradually increased .Conclusion The changes of bone metabolism markers in the elderly patients with hip fracture have their own characteristics dur‐ing the fracture healing period due to different genders .