七氟醚复合小剂量氯胺酮在小儿包皮环切术中的应用

目的：：研究七氟醚复合小剂量氯胺酮在小儿包皮环切手术中的应用效果。方法：40例择期行包皮环切手术的患儿随机分为七氟醚复合小剂量氯胺酮组(A组)和氯胺酮复合异丙酚组(B组)，每组20例。观察两组患儿从麻醉开始到意识消失时间、苏醒时间、麻醉时诱导顺从性、术中体动、苏醒期躁动、术后恶心呕吐的发生率。结果：与B组相比，A组患儿能较好接受麻醉，麻醉起效快、苏醒时间短，术中体动、苏醒期躁动发生率明显较低(P＜0.05)。两组术后恶心、呕吐发生率比较，差异无统计学意义(P＞0.05)。结论：七氟醚复合小剂量氯胺酮麻醉具有麻醉起效快、苏醒快、不良反应少的优点，能较好地用于小儿包皮环切手术。

APPLICATION OF SEVOFLURANE COMBINED SMALL DOES KETAMINE IN CIRCUMCISION FOR CHILDREN

ABSTRACT]Objective:To study the effects of sevolfurane combined small does ketamine in circumcision for children. Methods:40 children undergoing selective circumcision were randomly divided into A group (sevolfurane combined small does ketamine) and B group (ketamine combined propofol) with 20 children in each group. The induction time, recovery time, induced compliance, movement during operation, agitation, incidence of nausea and vomiting after operation of children were recorded.Results: Compared with children in B group, the induced compliance of children in A group was better, the induction time and the recovery time were shorter, the incidence of movement during operation and agitation were obviously lower (P<0.05). There had no statistical signiifcance about incidence of nausea and vomiting after operation between A group and B group (P>0.05).Conclusions:Sevolfurane combined small does ketamine is suitable for circumcision for children because of it’s quick onset, rapid recovery and less adverse effects.