| 脊髓腹角神经元共存NGF,BDNF,NT_3,NT_4和GDNF |
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| 引用本文： | 李维平,王廷华,徐蔚.脊髓腹角神经元共存NGF,BDNF,NT_3,NT_4和GDNF[J].昆明医学院学报,2000(3). |
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| 作者姓名： | 李维平 王廷华 徐蔚 |
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| 作者单位： | 深圳红十字会医院神经外科!深圳518035(李维平)，昆明医学院神经科学研究所!昆明650031(王廷华，徐蔚) |
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| 基金项目： | 云南省自然科学基金资助!( 99C0 0 0 6R) |
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| 摘 要： | 用NGF ,BDNF ,NT3,NT4 和GDNF抗血清 ,以免疫组织化学方法观察NGF ,BDNF ,NT3,NT4 及GDNF在成年猫L5脊髓腹角神经元是否共存 结果 :L5脊髓腹角神经元均含有上述被检测的 5种神经营养因子的免疫反应物 ,表明腹角神经元共存NGF ,BDNF ,NT3,NT4 及GDNF ,提示这 5种神经营养因子可能与脊髓腹角神经元的生理过程有关
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| 关 键 词： | 腹角神经元 NGF BDNF NT_3 NT_4与GDNF 共存 |
The Co-expression of NGF, BDNF, NT_3, NT_4 and GDNF in Neurons of Ventral Horn of Spinal Cord |
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| LI Wei-ping ,WANG Ting-hua ,XU Wei.The Co-expression of NGF, BDNF, NT_3, NT_4 and GDNF in Neurons of Ventral Horn of Spinal Cord[J].Journal of Kunming Medical College,2000(3). |
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| Authors: | LI Wei-ping WANG Ting-hua XU Wei |
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| Institution: | LI Wei-ping 1),WANG Ting-hua 2),XU Wei 2) |
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| Abstract: | The co-expression of nerve growth factor (NGF), brain derived neurotrophic factor(BDNF), Neurotrophin 3(NT 3), Neurotrophin 4(NT 4), and glia derived neurotrophic factor (GDNF) in ventral neuron of spinal cord was studied by ABC immunohistochemical method using antibody of NGF, BDNF, NT 3, NT 4 and GDNF. The distribution on the positive products of NGF, BDNF, NT 3, NT 4 and GDNF in segment L5 was observed in ventral neurons of spinal cord. The results demonstrated that ventral neurons in spinal cord contain all above investigated factors. It indicated that these factors are involved in the physiological process of ventral neuron in spinal cord. |
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| Keywords: | Ventral neuron of spinal cord NGF BDNF NT_3 NT_4 and GDNF Co-expression |
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