| 孕中期母血清生化指标的异常和不良妊娠结局关系的临床研究 |
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| 引用本文： | 李光辉,黄醒华. 孕中期母血清生化指标的异常和不良妊娠结局关系的临床研究[J]. 中华围产医学杂志, 1999, 2(3): 134-137 |
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| 作者姓名： | 李光辉 黄醒华 |
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| 作者单位： | 100006,北京,首都医科大学附属北京妇产医院 |
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| 摘 要： | 目的探讨孕中期血清生化指标异常与不良妊娠结局的关系。方法在孕中期对AFP、hCG及SP1等五项血清生化指标进行测定，采用群组研究方法。结果孕中期AFP、hCG及SP1的异常升高或降低是早产、IUGR及先兆子痫等不良妊娠结局的危险因素；联合筛查可提高阳性检出率。结论孕中期血清生化指标的筛查有可能成为预测不良妊娠结局的主要手段。
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| 关 键 词： | 甲胎蛋白类 促性腺激素类.绒毛膜 妊娠特异性β_1糖蛋白 妊娠中期 妊娠结局 |
Clinical Study on Associations between Second Trimester Maternal Serum Biochemical Markers and Adverse Pregnancy Outcomes |
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| LI Guanghui,HUANG Xinghua. Clinical Study on Associations between Second Trimester Maternal Serum Biochemical Markers and Adverse Pregnancy Outcomes[J]. Chinese Journal of Perinatal Medicine, 1999, 2(3): 134-137 |
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| Authors: | LI Guanghui HUANG Xinghua |
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| Abstract: | To determine whether abnormal maternal serum biochemical markersare associated with adverse pregnancy outcomes. Methods Cohort study was performed by detecting three serum biochemical markers (MsAFP, MshCG, MsSPl) in the second trimester. ResultsElevated or lowered serum biochemical marker levels increased risks for preterm delivery,IUGRand preeclampsia. Mu1tiple marker screenings enhanced screen-p0sitive rates. Conclusion Womenwith abnormal serum biochemical markers have high risk factors of adverse pregnancy outcomes andserum screenings may be one of the most important methods in predicting adverse pregnancy outcomes in the second trimester. |
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| Keywords: | Alpha-fetoproteins Gonadotropins Chorionic Pregnancy-specific beta1-glycoprotein Pregnancy trimester second Pregnancy outcome |
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