| 神经胶质瘤增殖特性与糖代谢机制的研究进展 |
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| 引用本文： | 王仕超,张焱如,张瑞剑. 神经胶质瘤增殖特性与糖代谢机制的研究进展[J]. 中华临床医师杂志(电子版), 2019, 13(6): 468-472. DOI: 10.3877/cma.j.issn.1674-0785.2019.06.013 |
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| 作者姓名： | 王仕超 张焱如 张瑞剑 |
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| 作者单位： | 1. 010018 呼和浩特，内蒙古农业大学生命科学院2. 010017 呼和浩特，内蒙古自治区人民医院神经外科 |
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| 摘 要： | 癌细胞的糖代谢异常是新近发现的肿瘤组织有别于正常组织的特征之一。研究表明葡萄糖作为主要能量供给者在许多方面与支持细胞功能的合成代谢途径有关，本文主要从有氧糖酵解、戊糖磷酸途径、三羧酸循环等不同糖代谢途径分析胶质瘤细胞增殖的特性，为脑胶质瘤的临床诊断与治疗提供科学的理论依据。
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| 关 键 词： | 神经胶质瘤 糖酵解 代谢重编程 |
| 收稿时间： | 2018-09-06 |
Advances in research of proliferative characteristics of glioma and mechanism of glucose metabolism |
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| Shichao Wang,Yanru Zhang,Ruijian Zhang. Advances in research of proliferative characteristics of glioma and mechanism of glucose metabolism[J]. Chinese Journal of Clinicians(Electronic Version), 2019, 13(6): 468-472. DOI: 10.3877/cma.j.issn.1674-0785.2019.06.013 |
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| Authors: | Shichao Wang Yanru Zhang Ruijian Zhang |
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| Affiliation: | 1. College of Life Sciences, Inner Mongolia Agricultural University, Hohhot 010018, China
2. Department of Neurosurgery, Inner Mongolia Autonomous Region People's Hospital, Hohhot 010017, China |
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| Abstract: | Abnormal glucose metabolism in cancer cells is one of the newly discovered characteristics of tumor tissue compared to normal tissue. Studies have shown that glucose as a major energy is, in many aspects, related to synthetic metabolic pathways that support cellular function. This article mainly discusses the characteristics of glioma cell proliferation from the perspective of aerobic glycolysis, the pentose phosphate pathway, and the Krebs cycle, with an aim to provide a scientific, theoretical basis for the clinical diagnosis and treatment of glioma. |
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| Keywords: | Glioma Glycolysis Metabolic reprogramming |
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