利多卡因胶浆对双J管留置术后尿及双J管细菌培养的影响

目的探讨利多卡因胶浆对双J管留置术后中段尿、双J管表面细菌培养结果及尿液中白细胞计数的影响。 方法将江西省玉山县人民医院2013年5月至2018年12月期间就诊的56例行输尿管双J管留置术患者随机分成2组，每组28例，对照组留置双J管时，双J管表面涂抹无菌生理盐水，治疗组留置双J管时在双J管表面均匀涂抹利多卡因胶浆。2组患者术前均行尿常规、尿培养检查，术后4周左右拔除双J管，剪取双J管中段作标本及尿液行细菌培养，采用χ²检验比较2组培养结果的阳性率的差异；采用t检验比较2组患者尿白细胞计数的差异。 结果置管前2组尿常规检查白细胞计数及中段尿培养阳性率比较［（1537±477）个/μl vs （1410±355）个/μl；10.7% vs 14.3%）］，差异均无统计学意义（t=0.780，P=0.439；χ²=0.163，P=0.686）。置管后对照组双J管培养及中段尿培养阳性率明显高于治疗组（25.0% vs 3.6%；28.0% vs 7.1%），差异均具有统计学意义（χ²=5.25，P=0.022；χ²=4.383，P=0.036）；2组患者尿液常规比较差异无统计学意义（t=0.089，P=0.929）。 结论利多卡因胶浆可降低双J管留置术后尿及双J管细菌培养的阳性率，可有效减低尿路感染。

Effect of lidocaine glue on bacterial culture of urine and double-J stent after double-J stent indwelling

ObjectiveTo investigate the effects of lidocaine glue on midstream urine culture and double-J stent bacterial culture after double-J stent indwelling. MethodsFifty-six patients with double-J stent placement in Yushan County people's Hospital of Jiangxi Province from May 2013 to December 2018 were randomly assigned into either a control group or a treatment group, with 28 cases in each group. In the control group, sterile saline solution was applied to the surface of the double-J stent, while the surface of double-J stent was evenly coated with lidocaine glue in the treatment group. Urinalysis and midstream urine culture were routinely tested before the operation. At around postoperative 4 weeks, urinalysis, midstream urine culture, and double-J stent bacterial culture immediately after stent removal were performed. The chi-square test was used to compare the positive rate of culture results between the two groups, and t-test was used to compare the difference of urine white blood cell count between the two groups. ResultsThere was no significant difference in preoperative urinalysis or midstream urine culture between the two groups (1537±477)/μl vs (1410±355)/μl, t=0.780, P=0.439; 10.7% vs 14.3%, χ²=0.163, P=0.686]. The positive rates of postoperative double-J stent culture and midstream urine culture in the control group were significantly higher than those in the treatment group (25.0% vs 3.6%, χ²=5.25, P=0.022; 28.0% vs 7.1%, χ²=4.383, P=0.036). There was no significant difference in postoperative urinalysis between the two groups (t=0.089, P=0.929). ConclusionLidocaine glue reduces the positive rates of postoperative midstream urine culture and double-J stent bacterial culture and may prevent urinary tract infection effectively.