高尿酸血症肾病的诊治进展

近年来人群平均血清尿酸水平及高尿酸血症的患病率逐渐升高，由于高尿酸血症发病隐匿，早期不易发现，一旦疾病进展可能导致不可逆性肾损伤，故需提高人群对本病的认识，争取早诊断、早治疗，并积极消除与血尿酸升高相关的代谢性危险因素。本文综述了高尿酸血症肾病的发病机制、临床特点及诊治进展，以提高对血尿酸水平的重视，为该病的防治提供依据。

Progress in diagnosis and treatment of hyperuricemic nephropathy

In recent years, the average serum uric acid level and the prevalence of hyperuricemia in the general population have gradually increased. As the onset of hyperuricemia is hidden, it is difficult to detect early. Once the disease progresses, it may lead to irreversible renal injury. Therefore, it is necessary to raise the awareness of hyperuricemia, strive for early diagnosis and treatment, and actively treat metabolic risk factors related to the increase of serum uric acid. This article will review the pathogenesis, clinical characteristics, diagnosis, and treatment of hyperuricemic nephropathy, in order to emphasize the importance of serum uric acid level and provide a basis for the prevention and treatment of this condition.