18F-FDG PET/CT在结直肠癌术后血清癌胚抗原阳性患者中的临床应用

目的探讨¹⁸F-FDG PET/CT检测结直肠癌术后血清癌胚抗原（CEA）阳性患者中复发和转移灶的价值。 方法回顾性分析60例结直肠癌术后CEA阳性且接受PET/CT检查的患者，将PET/CT检出结果与病理及随访结果进行比较。 结果¹⁸F-FDG PET/CT诊断阳性50例，假阳性1例；阴性10例，假阴性3例。PET/CT诊断结直肠癌术后CEA阳性患者复发和转移灶的灵敏度为94.2%（49/52），特异度为87.5%（7/8），阳性预测值为98.0%（49/50），阴性预测值为70.0%（7/10），准确率为93.3%（56/60）。 结论¹⁸F-FDG PET/CT在结直肠癌术后血清CEA阳性患者中有较高的临床应用价值，其对复发及转移灶的检测具有较高的灵敏度、特异度及准确率。

Clinical value of ~(18)F-FDG PET/CT in postoperative colorectal cancer patients with elevated serum carcinoembryonic antigen

ObjectiveTo explore the value of 18-fluorine flurodeoxyglucose (¹⁸F-FDG) positron-emission tomography (PET)/computed tomography (CT) in detecting recurrence and metastasis in postoperative colorectal cancer patients with elevated serum carcinoembryonic antigen (CEA). MethodsClinical data of 60 cases of colorectal cancer, including PET/CT, pathological, and follow-up results, were analyzed retrospectively. ResultsThere were 50 ¹⁸F-FDG PET/CT positive and 10 ¹⁸F-FDG PET/CT negative cases, including 1 false positive and 3 false negative cases. The sensitivity, specificity, positive predictive value, negative predictive value, and accuracy of ¹⁸F-FDG PET/CT in detecting recurrence and metastasis in postoperative colorectal cancer patients with elevated serum CEA were 94.2%(49/52), 87.5% (7/8), 98.0% (49/50), 70.0% (7/10), and 93.3% (56/60), respectively. Conclusion¹⁸F-FDG PET/CT has high clinical value in postoperative colorectal cancer patients with elevated serum CEA, and it has a high sensitivity, specificity, and accuracy in the detection of recurrence and metastasis.