月经紊乱者血清性激素变化的临床意义

 目的 探讨育龄期月经紊乱的不孕症患者血清性激素水平变化检测结果的临床意义。方法 将120例女性不孕症患者分为月经正常组和月经紊乱组,采用化学发光法测定患者血清LH、FSH、PRL、E₂ 、T、Pro值,与健康对照组女性血清性激素六项值进行比较分析。结果 月经正常组不孕症患者血清性激素六项水平与健康对照组女性血清性激素六项水平差异无统计学意义,月经紊乱组不孕症患者血清性激素LH(13.39±5.01) U/L]、FSH(12.88±3.11) U/L]、PRL(32.72±4.01) ng/ml]水平明显高于其他两组,差异有统计学意义(P<0.05),E₂、T、P水平三组间差异无统计学意义(P>0.05)。结论 分析血清性激素水平变化趋势对育龄期月经功能紊乱女性不孕症患者的临床诊断和治疗有指导意义。

Clinical correlations of changes in serum gonadal hormone levels in females with menstrual irregularity

Objective To analyze the clinical significance of serum gonadal hormone levels for diagnosis of female infertility due to menstrual irregularity.Methods 120 female infertility patients were divided into two groups:eumenorrhea group and paramenia group.The serum levels of LH,FSH,PRL,E2,Tand PRO of these patients were determined by chemiluminescence methods and compared with those of healthy women as control.Results There was no statistically significant difference of serum hormone levels between the eumenorrhea group and control.The serum levels of LH(13.39 ± 5.01) U/L]、FSH(12.88 ± 3.11) U/L] and PRL(32.72 ± 4.01) ng/ml] in paramenia group were much higher than those in the other two groups.The difference was of statistical significance (P ＜ 0.05),but there was no significant difference of serum levels of E2,T,and PRO between these three groups (P ＞ 0.05).Conclusions Analysis of the changes of serum hormone levels can facilitate clinical diagnosis and treatment of female infertility with menstrual irregularity.