超敏C反应蛋白检测在缺血性脑卒中诊治中的价值

目的：探讨超敏C反应蛋白在缺血性脑卒中患者诊治中的价值。方法选取120例缺血性脑卒中患者为疾病组，根据梗死程度的不同，将其分为轻度梗死47例，中度梗死35例，重度梗死38例；同时选择同期性别、年龄等一般资料近似的120名健康体检者设为对照组。检测所有疾病组患者治疗前后及健康体检者的超敏C反应蛋白，并比较分析检测结果，评价超敏C反应蛋白在缺血性脑卒中诊治中的价值。结果健康体检者、治疗前轻度梗死者、中度梗死者、重度梗死者的超敏C反应蛋白水平分别为（3.32±0.46） mg/L、（8.87±3.72）mg/L、（18.52±6.33）mg/L、（32.51±11.25）mg/L。缺血性脑卒中患者的超敏C反应蛋白水平明显高于健康体检受试者，且随着脑卒中梗死程度的加重，超敏C反应蛋白水平越高，组间比较差异均具有统计学意义（ P＜0.05）。治疗结束后患者的超敏C反应蛋白水平基本回复到正常水平。结论超敏C反应蛋白检测具有灵敏度高且快速的优点，可用于缺血性脑卒中患者的临床诊断及治疗效果评价。

Value of hs-CRP assay detection in the diagnosis and treatment of ischemic stroke

Objective To explore the value of high-sensitive C-reactive protein （ hs-CRP） in the diagnosis and treatment of ischemic stroke .Methods One hundred and twenty cases of ischemic stroke were selected as the disease group, and according to the different levels of infarction , those cases were divided into mild infarction group （47 cases）, moderate infarction group（35 cases）, severe infarction group（38 cases）; Meanwhile a healthy group was set up correspondingly by selecting 120 healthy cases with their general information , such as gender, age, etc, similar to which of the disease group .hs-CRP was detected in all disease groups before and after treatment and healthy group , and their test results were compared .Results The hs-CRP levels of the healthy group and which of the mild infarctions group, the moderate infarction group, the severe infarction group, before treatment were （3.32 ± 0.46）mg/L,（8.87 ±3.72）mg/L,（18.52 ±6.33）mg/L,（32.51 ±11.25）mg/L, respectively.Evidently the hs-CRP levels of ischemic stroke patients were higher than that of healthy people , further, more severe the infarction was, higher its hs-CRP levels was.The differences of above results between the disease groups and the healthy group were significant in statistics （ P〈0.05 ） .After treatment , the patients′hs-CRP levels basically returned to normal level.Conclusion The hs-CRP detection is high sensitive and fast .With that advantages, the method can be used in diagnosis of ischemic stroke and evaluation for its treatment effect .