目标性救治措施救治重症手足口病的临床效果分析

目的：探讨目标性救治措施救治重症手足口病（ HFMD）患儿的临床效果。方法对2012年在该院住院的138例重症手足口病患儿（研究组）采用目标性救治。同时将该院2010年未进行目标性救治（均按国家诊疗规范救治）的152例患儿作为对照组进行回顾性对比分析。结果研究组的病情加重率低于对照组（P＜0.01），但两组的抢救成功率和病死率比较差异无统计学意义（P均＞0.05）；研究组的症状消失时间和住院时间均短于对照组（ P＜0.05或＜0.01）；研究组的高血糖和神经系统后遗症发生率均低于对照组（ P均＜0.01）。结论目标性救治措施为重症HFMD的救治提供了系统性、可操作性的救治方案，可显著缩短临床症状消失时间和住院时间，降低高血糖和神经系统后遗症的发生率，改善预后。

Targeted treatment measures for children with severe hand- foot-mouth disease:an analysis of clinical efficacy

Objective To explore the clinical efficacy of targeted treatment measures for children with severe hand-foot-mouth disease （ HFMD ） .Methods On the basis of the mational standard for diagnosis and treatment of HFMD in the treatment group , 138 children with severe HFMD hospitalized in our hospital in 2012 were treated by targeted treatment measures;in the control group 152 children with severe HFMD were not treated by targeted treat-ment measures , and the clinical efficacy between two groups were retrospectively compared .Results The disease ex-acerbation rate in the treatment group was lower than that in the control group （ P〈0.01 ） , but the rescue success rate and case fatality rate were similar between the two groups （ P〉0.05 ）;the symptems disappearing time and length of hospital stay and breathing machine utilization rate in the treatment group were shorter than those in the control group （ P〈0.05 or 〈0.01 ）;the incidence of complications and sequela in the treatment group were lower than those in the control group （ P〈0.01 ） .Conclusion Targted treatment measares provide a systematic and operational scheme＆amp;nbsp;for treating severe HFMD ,can obviously shorten the clisappearing time of clinical symptoms and hospitalizationg time , reduce the incidence of hyperglycemia and the sequela of the nerves system ,and improve the prognosis .