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Hepatitis G virus
Authors:Reshetnyak Vasiliy Ivanovich  Karlovich Tatiana Igorevna  Ilchenko Ljudmila Urievna
Institution:1. Scientific Research Institute of General Reanimatology,Russia Academy of Medical Sciences,Moscow 107031,Russia
2. M.P.Chumakov Institute of Poliomyelitis and Viral Encephalitides,Russia Academy of Medical Sciences,Moscow 142782,Russia
Abstract:A number of new hepatitis viruses (G,TT,SEN) were discovered late in the past century.We review the data available in the literature and our own findings suggesting that the new hepatitis G virus (HGV),disclosed in the late 1990s,has been rather well studied.Analysis of many studies dealing with HGV mainly suggests the lymphotropicity of this virus.HGV or GBV-C has been ascertained to influence course and prognosis in the HIV-infected patient.Until now,the frequent presence of GBV-C in coinfections,hematological diseases,and biliary pathology gives no grounds to determine it as an "accidental tourist" that is of no significance.The similarity in properties of GBV-C and hepatitis C virus (HCV) offers the possibility of using HGV,and its induced experimental infection,as a model to study hepatitis C and to develop a hepatitis C vaccine.
Keywords:Hepatitis G virus  Markers of GBV-C  Epidemiology  Clinical manifestations
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