Hepatitis G virus |
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Authors: | Reshetnyak Vasiliy Ivanovich Karlovich Tatiana Igorevna Ilchenko Ljudmila Urievna |
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Institution: | 1. Scientific Research Institute of General Reanimatology,Russia Academy of Medical Sciences,Moscow 107031,Russia 2. M.P.Chumakov Institute of Poliomyelitis and Viral Encephalitides,Russia Academy of Medical Sciences,Moscow 142782,Russia |
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Abstract: | A number of new hepatitis viruses (G,TT,SEN) were discovered late in the past century.We review the data available in the literature and our own findings suggesting that the new hepatitis G virus (HGV),disclosed in the late 1990s,has been rather well studied.Analysis of many studies dealing with HGV mainly suggests the lymphotropicity of this virus.HGV or GBV-C has been ascertained to influence course and prognosis in the HIV-infected patient.Until now,the frequent presence of GBV-C in coinfections,hematological diseases,and biliary pathology gives no grounds to determine it as an "accidental tourist" that is of no significance.The similarity in properties of GBV-C and hepatitis C virus (HCV) offers the possibility of using HGV,and its induced experimental infection,as a model to study hepatitis C and to develop a hepatitis C vaccine. |
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Keywords: | Hepatitis G virus Markers of GBV-C Epidemiology Clinical manifestations |
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