高危人群阴道念珠菌带菌情况及抗真菌药物药敏分析

目的：为了解性病高危人群酵母菌的带菌情况和和对抗真菌药物的敏感性，方法：对167例特殊职业的性病高危女性人群进行了阴道分泌物涂片及培养检测，对分离出的临床菌株进行了8种常用抗真菌药物的敏感性检测。结果：性病高危女性人群中阴道念珠菌带菌率为12．1％，优势主要菌株仍以白念珠菌为主。结论：伊曲康唑、氟康唑，二性霉素B，制霉菌素，益康唑，酮康唑，咪康唑和5－氟胞啶的的药物敏感性显示，前4种均属高度敏感，后4种药物有不同程度的中度敏感与耐药。

Evaluation on Candida spp. infection and yeast sensitivity to antifungal agents in high risk female population

Objective:To determine the prevalence of Candida spp. infection and yeast sensitivity to antifugal agents among 167 women with high risk behaviors for the infection of STDs. Methods:The isolates from vaginal discharge were tested by microscope and cultured.Results:The prevalence rate of Cadida spp. was 12.1% (20/167) in this group of women.The main species of yeast was still Candida albicans and the strains were sensitive to most of antifungal agents. Conclusions :All of these strains isolated were sensitivity to itraconazole, fluconazole, amphotercin B and nystatin. Some of the strains showed less sensitivity to ketoconazole and econazole and a few of strains were resistant to miconazole and 5 fluorocytosine.