Operative Therapie des Vulva- und Vaginalkarzinoms

Context

Whereas decades ago, vulvar cancer was a tumor primarily diagnosed in elderly women, nowadays, this tumor is increasingly diagnosed. The rising incidence is mainly due to the increasing number of young women presenting with these tumors.

Methoden

Research of the literature and analysis of own results.

Results

Depending on the age of the women persistent infection with high risk human papillomavirus is responsible for the development of these lesions, in the young age group in about 30–50?% of the cases. More than 50?% (own data) of the tumors are located between the clitoris and urethra. Standard treatment is tumor resection with sufficient margin or (partial) vulvectomy and complete inguinofemoral lymphadenectomy or sentinel node biopsy in specialized centers. New therapy options are reconstruction of the vulva with local skin flaps to improve esthetic and functional outcome especially in young, sexually active women.