2009年我院抗菌药物用药强度分析

目的分析住院患者2009年抗菌药物用药强度。方法以限定日剂量（DDD）为单位,以DDD/100人天值计算抗菌药物使用强度。结果住院患者抗菌药物平均用药强度为88.32。二代头孢、三代头孢、其他β内酰胺类和头孢呋辛钠、头孢米诺钠、头孢哌酮舒巴坦钠分别位于各类别及各品种抗菌药物用药强度的前3位。各科室抗菌药物用药强度的中位数为78.37,泌尿外科、普外二科和腔镜外科位于前3位。结论医院可能存在抗菌药物用药过度、用药集中等问题,应进一步加强监督管理。

Antibiotics Use Density in the Hospital in 2009

Objective To investigate and analyze the use density of antibiotics of in-patients in the hospital in 2009.Method Taking defined daily dose（DDD） as the unit,the antibiotics use density（AUD） were calculated by the value of DDD per 100 days person.Result The mean value of AUD was 88.32.The second generation cephalosporins.The third generation cephalosporins and other-lactams antibiotics were the top 3 places in turn.The top three drugs about AUD were cefuroxime,cefminox sodium and cefoperazone/sulbactum.The median value of AUD was 78.37 in all clinical departments which urology department,the second general surgery department and the endoscopic surgery department ranked top three.Conclusion There may exist such problems as overmedication and dense medication in antibiotics usage in the hospital.It is necessary to strengthen the guidance.