过敏性皮肤疾病的两种过敏原检测方法的对比研究

目的分析不同检测方法应用在过敏性皮肤疾病过敏原检测中的临床效果。方法选择该院2014年3月至2015年3月门诊及住院病房收治的74例过敏性皮肤疾病患者作为研究对象,采用随机数字法将其分成免疫印迹法组与皮肤点刺法组,免疫印迹法组患者治疗前抽取静脉血进行免疫印迹法过敏原检测,皮肤点刺法组患者治疗前实施皮肤点刺法试验进行过敏原检测。结果免疫印迹法组检测的过敏原阳性率70.3%,而皮肤点刺法组检测的过敏原阳性率56.8%。免疫印迹法组的过敏原阳性率高于皮肤点刺法组,两者比较差异有统计学意义(P0.05)。结论对于过敏性皮肤疾病的过敏原检测,免疫印迹法在过敏原的筛选及其顺应性等方面要优于皮肤点刺试验。

Comparative study on two kinds of allergen detection methods for allergic skin diseases

Objective To investigate the clinical effect of different detection methods in the detection of allergens in allergic skin diseases .Methods Choose 74 cases of allergic skin disease patients in our hospital from March 2014 to March 2015 as the research object ,they were divided into two groups by random number method ,immunoblotting group and skin prick test group ,detected al-lergens of the two groups by immunoblotting and skin prick test before treatment .Results The positive rate was 70 .3% in immu-noblotting group ,and the positive rate was 56 .8% in skin prick test group .For allergens detection ,the positive rate was higher by using immunoblotting ,the differences between the two had significant difference(P<0 .05) .Conclusion Immunoblotting is better than the skin prick test for allergen detection in allergic skin diseases .