银屑病早发型和晚发型的研究

目的 探讨中国人银屑病是否也存在早发型、晚发型的差别以及这种分型方法的合理性。方法 统计1632例寻常型银屑病患者发病年龄的分布,按照就诊时病情轻重、随访时病情轻重及是否有家族史,做统计学分析。并结合我国1984年全国调查资料进行探讨。结果 本组资料和1984年全国大规模调查资料均显示寻常型银屑病发病年龄只有一个高峰,没有双峰现象。本组资料虽然显示发病年龄早者有家族史的患者多,病情轻重与发病年龄也有一定关系,但都没有比较明确的年龄分界。结论 银屑病按照发病年龄分型除了说明早发者有较高的家族史外,对指导临床并无多大价值。

Study and Evaluation on Early and Late Onset Psoriasis

Objective To verify whether there is any difference between early-onset and late onset subtypes of psoriasis and the rationality of this classification. Methods A total of 1 632 patients with psoriasis vulgaris were included in this study. The distribution of age at onset was calculated. The disease severity at first visit and follow up, and the family history were assessed according to different ages at onset. The results were evaluated in the light of the data from a national psoriasis survey in 1984. Results There was only one peak regarding to the age at onset in psoriasis vulgaris, rather than two peaks according to our study, it was consistent with the results of the national large scale survey reported in 1984. It was found that the earlier the age at onset, the more frequently the patient had positive family history. There was some relationship between the disease severity and the age at onset, however, a clear cut age at onset by which the disease serverity could be determined was not identified in this study. Conclusion It is suggested that the early age at onset be related only to the increased possibility of family history. Its value in clinical management is not significant.