妊娠合并乙型肝炎病毒感染对妊娠结局的影响

目的：探讨妊娠合并乙肝病毒感染影响妊娠结局的因素。方法：采用回顾性方法分析了1989年1月至1992年12月期间183例妊娠期存在乙肝病毒感染者的妊娠结局。结果：(1)妊娠合并乙肝病毒感染各并发症的发生率：胎膜早破21．31％，早产12．02％，妊高征10．38％，胎儿窘迫12．02％，产后出血3．23％，新生儿窒息10．38％；(2)妊娠合并乙肝病毒感染有肝功能异常组与肝功能正常组相比其早产(28．17％)、妊高征(22．54％)、胎儿窘迫(25．35％)、产后出血(8．45％)发生率均明显增高，新生儿出生体重则明显降低。结论：妊娠合并乙肝病毒感染，易发生胎膜早破、早产、妊高征、胎儿窘迫及产后出血，肝功能异常对这些妊娠并发症的发生有显著影响。应重视该类病例的治疗。

Analysis of pregnancy outcome with hepatitis B virus infection

Objective To investigate the pregnancy outcome in wom en with hepatitis B infection. Methods The clinical data of 183 cases with hepatitis B infection during pregnancy from January 1989 to December 1992 were retrospectively analyzed. Results The incidences of pregnancy complication are:premature rupture of membranes,21 3%;p reterm birth,12 02%;pregnancy induced hypertension(PIH),10 38%;fetal distress, 12 02%;newborn asphyxia,10 38%;postpartum haemorrhagia,3 23%.Compared with th e group of normal hepatic function,the incidences of pregnancy complication in t he hepatic dysfunction group were higher,but the infant birth weight lower. Conclusion The pregnancy with hepatitis B virus infection more frequently results in premat ure rupture of membrane,preterm birth,PIH,fetal distress and postpartum haemorr hagia.Hepatic dysfunction may affect the outcome of pregnancy.Intensive car e should be paid to such patients.