经内镜胆管细胞刷检和组织活检诊断胆管癌的价值

目的评价经内镜胆管细胞刷检、组织活检诊断胆管癌的价值。方法对30例经手术或临床随访确诊为胆管癌的患者行胆管细胞刷检、组织活检、细胞刷检＋组织活检联合检查。结果30例胆管癌患者行胆管细胞刷检阳性率为36．7％，胆管组织活检阳性率为43．3％，细胞刷检和组织活检阳性率差异无统计学意义（χ^2=0．278，P=0．598）。细胞刷检＋组织活检联合检查阳性率为64．1％，联合检查与单独细胞刷检比较差异有统计学意义（χ^2=4．267，P=0．039），联合检查与单独组织活检比较差异无统计学意义（χ^2=2．411，P=0．121）。结论经内镜组织活检联合细胞刷检能进一步提高胆管癌诊断的阳性率，对诊断胆管癌有重要的价值。

Values of endoscopic retrograde brush cytology and endoscopic retrograde forceps biopsy in the diagnosis of cholangiocarcinoma

Objective To evaluate the values of endoscopic retrograde brush cytology （ERBC） and endoscopic retrograde forceps biopsy （ERFB） in the diagnosis of cholangiocarcinoma. Methods 30 patients with cholangiocarcinoma confirmed by operation or clinical follow-up were checked with ERBC, ERFB and the combination of ERBC and ERFB. Results The positive rate was 36.7% by ERBC, and 43.370 by ERFB, and there was no statistical significance in the positive rates between the two methods （χ^2=0.278, P-0.598）. The positive rate was 64.1% by the combination of ERBC and ERFB, and there was statistical significance between the combination methods and ERBC （χ^2=4.267, P=0.039）, but there was no statistical significance between the combination methods and ERFB （χ^2=2.411, P=0.121）. Conclusion The combination of ERBC and ERFB can improve the positive rate and has great value in the diagnosis of cholangiocarcinoma.