闭经的诊断进展

女性正常月经依赖于下丘脑、垂体和卵巢及其激素诱导的子宫内膜之间的相互协调作用，其中任何一个方面出现功能障碍都可能导致闭经，影响生育。引起闭经的病因众多，明确诊断闭经的病因是治疗的关键。病史、体格检查、内分泌功能检查和辅助检查相结合可对闭经进行全面诊断。临床上最常见的闭经病因为下丘脑病变、多囊卵巢综合征、高催乳素血症和卵巢衰竭，综述临床常见闭经病因的诊断进展。

Progress in Diagnosis of Amenorrhea

The normal menstruation depends on the intercoordination between the hypothalamus- pituitary- ovary system and the endometrium induced by ovarian hormone. Dysfunction of any aspect will result in amenorrhea，and then affect fertility. There are many causes of amenorrhea. The key of successful treatment is the clarified diagnosis. The overall diagnosis of amenorrhea should combine history，physical examination，endocrine and auxiliary examination. The most common causes of amenorrhea are hypothalamic amenorrhea，polycystic ovary syndrome，hyperprolactinemia and premature ovarian failure. This review discussed the etiological diagnosis of amenorrhea.