| 足细胞损伤与肾小球疾病 |
| |
| 引用本文： | 梁燕,程丽静,黄海长.足细胞损伤与肾小球疾病[J].中国病理生理杂志,2005,21(9):1864-1866. |
| |
| 作者姓名： | 梁燕 程丽静 黄海长 |
| |
| 作者单位： | 1大连医科大学第二附属医院肾内科， 辽宁 大连 116027；2北京大学第一医院肾内科, 北京 100034 |
| |
| 摘 要： | 足细胞（podocyte），即肾小球脏层上皮细胞，它附着于肾小球基底膜（glomerular basement membrane，GBM）的外侧，连同GBM和毛细血管内皮细胞一起，构成肾小球血液滤过屏障。足细胞这一独特的解剖位置，使得其体内研究较为困难；又由于正常成年机体的肾脏足细胞是一种终末分化细胞，体外培养的原代细胞不能增殖，
|
| 关 键 词： | 足细胞 肾小球 |
| 文章编号： | 1000-4718（2005）09-1864-04 |
| 收稿时间： | 2003-12-23 |
| 修稿时间： | 2003-12-232004-04-23 |
Podocyte injury and glomerular diseases |
| |
| LIANG Yan,Cheng Li-jing,HUANG Hai-chang.Podocyte injury and glomerular diseases[J].Chinese Journal of Pathophysiology,2005,21(9):1864-1866. |
| |
| Authors: | LIANG Yan Cheng Li-jing HUANG Hai-chang |
| |
| Institution: | 1Division of Nephrology, Dalian Medical University Second Hospital, Dalian 116027, China；2Division of Nephrology, Peking University First Hospital, Beijing 100034, China |
| |
| Abstract: | As constructive cells of the glomerular filtration barrier, podocytes plays an essential role in the maintenance of the glomerular blood filtration, and also in the prevention of protein loose from blood. Many factors cause podocyte injury, and consequently contribute to the onset and progression of glomerular lesions. This review focuses on relationship between podocyte injury and glomerular disease. |
| |
| Keywords: | Podocytes Kidney glomerulus |
| 本文献已被 维普 万方数据 等数据库收录！ |
| 点击此处可从《中国病理生理杂志》浏览原始摘要信息 |
| 点击此处可从《中国病理生理杂志》下载免费的PDF全文 |
