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Glycan-Based Near-infrared Fluorescent (NIRF) Imaging of Gastrointestinal Tumors: a Preclinical Proof-of-Concept In Vivo Study |
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| Authors: | Houvast Ruben D. Baart Victor M. Bhairosingh Shadhvi S. Cordfunke Robert A. Chua Jia Xin Vankemmelbeke Mireille Parsons Tina Kuppen Peter J. K. Durrant Lindy G. Vahrmeijer Alexander L. Sier Cornelis F. M. |
| Affiliation: | 1.Department of Surgery, Leiden University Medical Centre, Albinusdreef 2, 2333 ZA, Leiden, the Netherlands ;2.Department of Immunohematology and Blood Transfusion, Leiden University Medical Centre, Leiden, the Netherlands ;3.Scancell Limited, University of Nottingham Biodiscovery Institute, University Park, Nottingham, UK ;4.Division of Cancer and Stem Cells, School of Medicine, University of Nottingham Biodiscovery Institute, University Park, Nottingham, UK ;5.Percuros BV, Leiden, the Netherlands ; |
| Abstract: | Molecular Imaging and Biology - Aberrantly expressed glycans in cancer are of particular interest for tumor targeting. This proof-of-concept in vivo study aims to validate the use of aberrant Lewis... |
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