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Enhanced lysosomal function is critical for paclitaxel resistance in cancer cells: reversed by artesunate
Authors:Zhe Li  Yu-ting Zhu  Min Xiang  Jun-lan Qiu  Shou-qing Luo  Fang Lin
Institution:1.Department of Pharmacology, Laboratory of Aging and Nervous Diseases (SZS0703), Soochow University School of Pharmaceutical Science, Suzhou, 215123 China ;2.Suzhou Vocational Health College, Suzhou, 215123 China ;3.Department of Oncology, The Affiliated Suzhou Science & Technology Town Hospital of Nanjing Medical University, Suzhou, 215123 China ;4.Peninsula Medical School, University of Plymouth, Research Way, Plymouth, PL6 8BU UK
Abstract:
Keywords:artesunate  cisplatin-resistant human lung adenocarcinoma cells (A549/DDP)  paclitaxel-resistant human lung adenocarcinoma cells (A549/TAX)  doxorubicin-resistant human breast cancer cells (MCF-7/ADR)  lysosome  TFEB
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