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The Effect of Chirality on the Application of 5-[18F]Fluoro-Aminosuberic Acid ([18F]FASu) for Oxidative Stress Imaging |
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| Authors: | Čolović Milena Yang Hua Merkens Helen Colpo Nadine Bénard François Schaffer Paul |
| Affiliation: | 1.Life Sciences Division, TRIUMF, 4004 Wesbrook Mall, Vancouver, BC, V6T 2A3, Canada ;2.Molecular Oncology, British Columbia Cancer Research Centre, 675 W 10th Ave, Vancouver, BC, V5Z 1L3, Canada ;3.Department of Radiology, Faculty of Medicine, University of British Columbia, Vancouver, Canada ;4.Department of Chemistry, Faculty of Science, Simon Fraser University, Vancouver, Canada ; |
| Abstract: | Molecular Imaging and Biology - The cystine transporter, system xC-, plays a crucial role in sustaining redox homeostasis and is reported to be overexpressed in several cancer subtypes.... |
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