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Confirmation of Specific Binding of the 18-kDa Translocator Protein (TSPO) Radioligand [18F]GE-180: a Blocking Study Using XBD173 in Multiple Sclerosis Normal Appearing White and Grey Matter
Authors:Sridharan  Sujata  Raffel  Joel  Nandoskar  Ashwini  Record  Chris  Brooks  David J  Owen  David  Sharp  David  Muraro  Paolo A  Gunn  Roger  Nicholas  Richard
Institution:1.Division of Brain Sciences, Faculty of Medicine, Imperial College London, Hammersmith Hospital Campus, Burlington Danes Building, Du Cane Road, London, W12 0NN, UK
;2.Institute of Clinical Medicine, Aarhus University, Aarhus, Denmark
;3.Institute of Neuroscience, Newcastle upon Tyne University, Newcastle upon Tyne, UK
;4.Invicro Ltd., London, UK
;
Abstract:Molecular Imaging and Biology - Measurements of non-displaceable binding (VND) of positron emission tomography (PET) ligands are not often made in vivo in humans because they require ligands to...
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