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A naturally hypersensitive porcine model may help understand the mechanism of COVID-19 mRNA vaccine-induced rare (pseudo) allergic reactions: complement activation as a possible contributing factor
Authors:Dézsi  László  Mészáros  Tamás  Kozma   Gergely  H-Velkei  Mária  Oláh  Csaba Zs.  Szabó   Miklós  Patkó   Zsófia  Fülöp  Tamás  Hennies   Mark  Szebeni   Miklós  Barta   Bálint András  Merkely   Béla  Radovits   Tamás  Szebeni   János
Affiliation:1.Nanomedicine Research and Education Center, Department of Translational Medicine, Semmelweis University, Budapest, Hungary
;2.SeroScience LCC, Budapest, Hungary
;3.Department of Neurosurgery, BAZ County Central Hospital and Borsod County University Teaching Hospital, Miskolc, Hungary
;4.Department of Pulmonology, BAZ County Central Hospital and Borsod County University Teaching Hospital, Miskolc, Hungary
;5.Department of Radiology, BAZ County Central Hospital and Borsod County University Teaching Hospital, Miskolc, Hungary
;6.TECOdevelopment GmbH, Rheinbach, Germany
;7.Heart and Vascular Center, Semmelweis University, Budapest, Hungary
;8.Department of Nanobiotechnology and Regenerative Medicine, Faculty of Health, Miskolc University, Miskolc, Hungary
;
Abstract:GeroScience - A tiny fraction of people immunized with lipid nanoparticle (LNP)-enclosed mRNA (LNP-mRNA) vaccines develop allergic symptoms following their first or subsequent vaccinations,...
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