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Targeting Phosphatidylethanolamine with Fluorine-18 Labeled Small Molecule Probe for Apoptosis Imaging |
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| Authors: | Yuan Gongjun Liu Shaoyu Ma Hui Su Shu Wen Fuhua Tang Xiaolan Zhang Zhanwen Zhao Jing Lin Liping Xiang Xianhong Nie Dahong Tang Ganghua |
| Affiliation: | 1.Department of Nuclear Medicine and Medical Imaging, the First Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510080, China ;2.Guangdong Engineering Research center for Translational Application of Medical Radiopharmaceuticals, Sun Yat-sen University, Guangzhou, 510080, China ;3.School of Materials and Energy, South China Agricultural University, Guangzhou, 510642, China ;4.Department of Radiation Oncology, the First Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510080, China ;5.Nanfang PET Center and Department of Nuclear Medicine, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China ; |
| Abstract: | Molecular Imaging and Biology - Externalization of phosphatidylethanolamine (PE) in dying cells makes the phospholipid an attractive target for apoptosis imaging. However, no ideal PE-targeted... |
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