曲马多对鼻内窥镜术患者术后躁动的防治效果

目的了解曲马多对鼻内窥镜术患者术后躁动的防治效果。方法将128例在该院行鼻内窥镜术的患者随机分为观察组和对照组各64例。对照组在全麻过程中按常规进行诱导、麻醉;观察组则在术前予以曲马多注射液2mg/kg肌内注射,其余同对照组。以术后躁动发生率、苏醒时间及平均动脉压(MBP)、心率(HR)为观察指标,对2组进行比较。结果观察组躁动发生率为15.6%,低于对照组的39.1%;术后0.5、1、2h各时点MBP、HR低于对照组,差异均有统计学意义(P<0.05和P<0.01)。观察组平均苏醒时间为(15.08±7.5)min,对照组为(17.32±6.95)min,2组比较差异无统计学意义(P>0.05)。结论曲马多对鼻内窥镜术后患者的躁动有预防作用,对术后血流动力学有稳定作用。

Effect of tramadol in the prevention and treatment of restlessness of postoperative patients with nasal endoscopy

Objective To understand the effect of prevention and treatment of agitation with tramadol injections on patients with nasal endoscopy. Methods 128 cases who needed to accept nasal endoscopy in our hospital were randomly di- vided into observation group and control group, each group of 64 cases. The control group received induction, anesthesia accord- ing to conventional method during general anesthesia. Besides control groups procedure , the observation group were given tram- ado1 injections of 2mg/kg before operation. The incidence of postoperative agitation, recovery time, mean blood pressure （MBP） and heart rate （HR） of 2 groups were observed and compared. Results The incidence of postoperative agitation of observation group （ 15.6% ） was lower than that of the control group （39.1%） ;the MBP,HR of observation group 0.5,1,2 hours after operation was lower than that of the control group, and the differences were statistically significant （P 〈 0.05, P 〈 0.01 ）. The recovery time of the observation was （ 15.08 ＋ 7.5 ） min, the recovery time of the control was （ 17.32 ＋ 6.95 ） min, and there was no significant difference between 2 groups （P 〉 0.05 ）. Conclusion It is effective to prevent the agitation of the patients with nasal endoscopy with tramadol injection, and which has a stabilizing effect for postoperative haemodynamics of patients.