冠心病心绞痛证型分布及辨证规律系统综述

主要目的]分析冠心病心绞痛临床中医证型分布规律。资料来源]中国生物医学文献数据库(CBM disc)、中国学术期刊全文数据库(CNKI)。选择文献量及依据]以"冠心病"、"心绞痛"、"心肌缺血"、"胸痹"、"心痛"、"胸痹心痛"一次检索;以"证"、"辨证"、"证候"、"证型"、"临床研究"二次检索,2002年1月至2011年12月公开发表相关文献。初检992篇中文文献,阅读文献题名摘要及全文,根据纳入和排除标准共排除843篇,确定纳入149篇,各证型有具体病例数据文献50篇,共记录病例11542例。数据提炼规则及应用方法]制定"冠心病心绞痛文献调查表",主要内容包括文献编号、题目、作者、作者单位、出版时间、期刊来源、诊断标准、样本量、中医辨证分型等字段,采用双录入方法录入Excel表建立数据库。采用SPSS17.0统计软件,计数资料采用χ2检验。使用Excel2010软件建立数据库,统计证型例数频率。数据综合得出结果与结论]冠心病心绞痛的辨证分型尚无统一标准,各证型发病率由高到低前六位分别为心血瘀阻证、痰阻心脉证、心气亏虚证、心阳亏虚证、气阴两虚证、气虚血瘀证,证型发病与地域差异有关。未来展望]未来有必要以中医辨证理论为指导,运用统计学和流行病学方法开展对冠心病心绞痛中医证候规范化及其流行病学的多中心研究。

Systematic Review of Distribution of Syndrome Types And Law of Syndrome Differentiation of Coronary Angina Pectoris

Main Object]To analyze the regularities of distribution of clinical syndrome types of TCM with angina pectoris of coronary heart disease（CHD）.Data Source]China Biology Medicine disc（CBM disc）,China Academic Journal Full-text Database（CNKI）.Literature Selection and Criterion]Search the published literature from January 2002 to December 2011 using＂CHD＂,＂angina＂,＂myocardial ischemia＂, ＂Thoracic Obstruction Syndrome＂,＂cardiodynia＂for the first time to retrieve,and ＂Syndromes＂,＂syndrome differ classification＂,＂clinical study＂for the second time to retrieve.We found total of 992 references,by reading literature,and then according to the inclusion criteria and exclusion criteria were ruled out 843,149 have syndrome differentiation typing,50 have case load with 11542.Data Extracting and Method]Make a questionnaire about angina,which main contents include the document number,title,author,author＇s unit, publishing time,journal source,diagnostic criteria,sample size,type of syndrome and set up the database with method of two people with two computers input input Excel table.Results and Conclusions]There was no uniform standard about syndrome type of angina pectoris of CHD.The incidence of syndrome type from high to low were Stagnation of Heart- blood,Stagnation of phlegm in the vessel of Heart,Deficiency of Heart Qi,Deficiency of Heart Yang,deficiency of both qi and yin and Qi deficiency and blood stasis,the morbidity of syndrome type associated with regional differences.Future Prospects]It is necessary to use of traditional Chinese medicine theory as the guidance,use of modern statistical and epidemiological research methods to carry out multi-center study of syndromes standardization and epidemiology of angina.