冲顶式上颌窦底提升植骨同期牙种植的实验研究

[目的]探讨用Summer's骨凿冲顶提升上颌窦底后窦底骨质和黏骨膜改变情况以及种植体与周围组织结合生物学变化,为临床应用该项技术提供进一步可靠的实验依据.[方法]16只狗随机分为提升高度不同(2 mm、4 mm)2组,每只狗植入种植体4枚,一侧植骨,一侧不植骨,在不同时间(3、6、12、24周)取材.标本经大体观察,放射检查,组织学检查,四环素荧光检查,抗BMP-2免疫组化检测.[结果]移植骨愈合良好,种植体形成骨结合,提升4 mm不植骨种植体顶端无骨形成.[结论]上颌窦提升2 mm种植体顶端有骨存在,提升4 mm时,植入种植体顶端多数情况下无骨存在.

Experimental Study on Maxillary Sinus Elevation with Simultaneous Implantation with Osteotome

[Objective]By ways of examining the alternation of the bone together with its membrane in the sinus floor, the biological change of the integration among the implants and circumferential tissue in dogs underwent maxillary sinus elevation with Summer's osteotome, to provide further reliable experimental evidences to such technique in clinical application. [Methods]We randomly divided 16 dogs into two groups according to various elevating height (2, 4 mm). Each dog had 4 implants inserted, unilaterally bone grafted. Samples were taken postoperatively at the time of 3, 6, 12, and 24 weeks, respectively, evaluated and analyzed by general observation, radiographic observation, histological examination, tetracycline staining test, and immunohistochemical test on BMP-2. [Results]Grafted bones recovered in good condition; the integration between the implants and bone was firm. No bone formed on the top of implants with 4 mm elevation without bone graft. [Conclusions]Bone exists on the top of the implants where maxillary sinus was elevated by 2 mm whereas there is little bone existing on the top of the implants in major cases when maxillary sinus was elevated by 4 mm.