| 推按运经仪对家兔胆囊壁胆囊收缩素受体基因表达的影响 |
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| 引用本文： | 李健,范丽丽,黄彬,郭绍举,张竞超,刘心亮.推按运经仪对家兔胆囊壁胆囊收缩素受体基因表达的影响[J].中国中西医结合消化杂志,2012,20(8):342-343,346. |
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| 作者姓名： | 李健 范丽丽 黄彬 郭绍举 张竞超 刘心亮 |
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| 作者单位： | 广州中医药大学深圳临床医学院脾胃病科,广东深圳,518033 |
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| 基金项目： | 国家中医药管理局十二·五重点专科资助项目 |
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| 摘 要： | 目的]观察推按运经仪对家兔胆囊壁胆囊收缩素(CCKA)受体基因表达的影响及其作用机制.方法]将30只胆囊结石家兔随机分为2组,各15只,对照组不行推按运经仪治疗；实验组空腹时每日行推按运经仪治疗,观察2组胆囊体积和胆囊壁CCK-A受体基因表达的差异.结果]实验组胆囊体积明显小于对照组,而胆囊平滑肌CCK A受体基因表达明显大于对照组,差异均有统计学意义(P＜0.05).结论]推按运经仪治疗胆囊结石可增强胆囊壁CCK-A受体基因表达,加强胆囊收缩,可能是其防治胆囊结石的作用机制之一.
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| 关 键 词： | 胆囊结石 推按运经仪 胆囊壁胆囊收缩素受体 |
Effect of pushing-palpating channel-moving apparatus on expression of CCK-AR mRNA in gallbladder smooth muscle of rabbits |
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| LI Jian
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FAN Li-li
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HUANG Bin
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GUO Shao-ju
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ZHANG Jing-chao
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LIU Xin-liang.Effect of pushing-palpating channel-moving apparatus on expression of CCK-AR mRNA in gallbladder smooth muscle of rabbits[J].Chinese Journal of Integrated Traditional and Western Medicine on Digestion,2012,20(8):342-343,346. |
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| Authors: | LI Jian FAN Li-li HUANG Bin GUO Shao-ju ZHANG Jing-chao LIU Xin-liang |
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| Institution: | (Spleen and Stomach Diseases,Clinical Medical College of Shenzhen,Guangzhou University of Traditional Chinese Medicine,Shenzhen 518033,China) |
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| Abstract: | Objective]To observe the influence of the pushing-palpating channel-moving apparatus on expression of CCK-AR mRNA.Methods]Pushing-palpating channel-moving apparatus was used to treat rabbits with cholecystothasis in different groups.CCK-AR mRNA expression in the gallbladder smooth muscle was detected.Results]The pushing-palpating channel-moving apparatus treatment enhanced the expression of CCK-AR mRNA in the gallbladder smooth muscle,strengthened gallbladder shrinkage function and reduced the size of the gallbladder.Conclusion]The pushing-palpating channel-moving apparatus strengthens gallbladder shrinkage function via increasing the expression of CCK-AR mRNA in the gallbladder smooth muscle,which may be one of the mechanisms in prevention of gallstone recurrence. |
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| Keywords: | pushing-palpating channel-moving apparatus the expression of CCK-AR mRNA in the gallbladder wall rabbits |
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