青蒿琥醋联合奎宁马斯治疗疟疾90例临床观察

目的：观察青蒿琥酯联合奎宁马斯治疗疟疾的临床效果。方法：将180例疟疾患者根据入院顺序分为治疗组与对照组各90例，2组均给予奎宁马斯针剂静脉滴注治疗，治疗组同时给予青蒿琥酯针剂静脉滴注。结果：治疗组显效率显著高于对照组（P〈0．05），2组总有效率差异无统计学意义（P〉0．05）。治疗组平均退热时间、平均原虫转阴时间均比对照组短（P〈0．05），24小时平均原虫下降率高于对照组（P〈0．05）；不良反应明显少于对照组（P〈0．05）。结论：青蒿琥酯联合奎宁马斯治疗疟疾疗效显著，可改善临床症状，且安全性好。

Clinical Observation on Treating 90 Cases of Malaria with Artesunate and Quinimax Injection

Objective： To explore clinical effects ofartesunate and quinimax in treating malaria. Method： All 180 patients were divided into treatment group and control group in the order of hospitalization. Both groups received intravenous quinimax injection. Threatment group were given with intravenous artesunate. Result： Effectual rate of treatment group was higher than that of control group（P〈0.05）, comparison of both groups showed no statistical meaning in total effective rate （P〉0.05）. Average time ofdefervescence and mean time of parasite clearance of treatment group were shorter than that of control group （P〈0.05）, 24 h mean decline rate of parasite of treatment group was higher than that of control group（P〈0.05）, Adverse reactions were remarkably less than that of control group （P〈0.05）. Conclusion： Artesunate and quinimax injection are effective and safe in treating malaria and could improve clinical symptoms.