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复方甘草酸苷治疗妊娠合并慢性乙型肝炎疗效观察
引用本文:聂燕,杨龙涛.复方甘草酸苷治疗妊娠合并慢性乙型肝炎疗效观察[J].中国药房,2007,18(29):2290-2291.
作者姓名:聂燕  杨龙涛
作者单位:东南大学医学院附属南京第二医院,南京市,210003
摘    要:目的:观察复方甘草酸苷治疗妊娠合并慢性乙型肝炎的疗效。方法:随机选择279例妊娠合并慢性乙型肝炎患者,静脉滴注复方甘草酸苷,qd,15d为1个疗程,观察治疗前、后患者及胎儿相关指标的变化情况。结果:治疗后肝功能有明显改善,与治疗前比较有显著性差异(P<0.01)。胎儿与正常同孕龄者发育相仿,无显著性差异(P>0.05),治疗期间无明显不良反应发生。结论:复方甘草酸苷治疗妊娠合并慢性乙型肝炎安全、有效。

关 键 词:复方甘草酸苷  慢性乙型肝炎  妊娠  疗效
文章编号:1001-0408(2007)29-2290-02
收稿时间:2006-11-22
修稿时间:2007-01-16

Compound Glycyrrhizin for Pregnant Women Complicating Chronic Type B Hepatitis: Observation of Curative Effect
NIE Yan,YANG Longtao.Compound Glycyrrhizin for Pregnant Women Complicating Chronic Type B Hepatitis: Observation of Curative Effect[J].China Pharmacy,2007,18(29):2290-2291.
Authors:NIE Yan  YANG Longtao
Institution:The Affiliated Nanjing No.2 Hospital of Medical College, Southeast University, Nanjing 210003, China
Abstract:OBJECTIVE: To observe the curative effect of Compound Glycyrrhizin in treating pregnant women complicating chronic type B hepatitis.METHODS: 279 pregnant women complicating chronic type B hepatitis were randomly selected to receive compound glycyrrhizin by iv gtt q.d with 15 days as a course of treatment,with the change of the related parameters in the pregnant women and their fetuses before and after treatment observed.RESULTS: The liver function had a significant improvement after treatment as compared with pre-therapy(P<0.01).The development of these fetuses was similar to those fetuses that with normal gestational age(P>0.05).No obvious adverse reactions were noted during treatment.CONCLUSION: Compound Glycyrrhizin is safe and effective in the treatment of pregnant women complicating chronic type B hepatitis.
Keywords:Compound Glycyrrhizin  Chronic type B hepatitis  Pregnancy  Curative effect
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