| 加或不加泰素的CAF方案治疗转移性乳腺癌疗效观察 |
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| 引用本文： | 肖宏卫,吴灿,李硕,余汉毅,李远东. 加或不加泰素的CAF方案治疗转移性乳腺癌疗效观察[J]. 医学理论与实践, 2005, 18(6): 645-646 |
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| 作者姓名： | 肖宏卫 吴灿 李硕 余汉毅 李远东 |
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| 作者单位： | 广东省韶关市第一人民医院肿瘤外科,512000 |
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| 摘 要： | 目的:比较CAF加泰素(Paclitaxel、PLL、P)方案与单用CAF方案治疗晚期乳腺癌的疗效、生存率及毒性反应情况。方法:共治疗晚期乳腺癌52例,其中CAF方案26例,CAF加泰素方案26例。疗效评价按WHO标准评价。结果:CAF组及CAF加泰素组有效率分别为50.0%和65.4%,P<0.05,毒性反应CAF加泰素组胃肠道反应及白细胞抑制均明显高于CAF组,P<0.05。结论:两组结果相比疗效有明显差异,毒性反应有显著性差异,须重视。
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| 关 键 词： | 泰素 CAF方案 晚期乳腺癌 化疗 |
| 文章编号： | 1001-7585(2005)06-0645-02 |
| 修稿时间： | 2005-01-10 |
Compared CAF Combined with or without Paclitaxel in the Treatment of Advanced Breast Carcinoma |
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| Abstract: | Objective:To compare the efficacy and toxicity of regimen CAF with regimen CAPF.Methods:52 patients with breast cancer were enrolled , 26 patients were given CAF and the other 26 were given CAPF chemotherapy。 The treatment results were assessed according to WHO criteria.Results:The response rate of CAF and CAPF regimes are 50.0% and 65.4% (P<0.05). Compared with CAF, CAPF had higher toxic effects on digestive and hemopoietic systems(P<0.05). Conclusion:The results show that the response rate and the toxicity between the two groups are both statistically significance. |
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| Keywords: | Paclitaxel regimen CAF Breast carcinoma Chemotherapy |
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