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The mobilization of autologous bone marrow stem cells in the treatment of heart failure with Chinese medicine
Authors:Kui-wu Yao  Liang-deng Zhang  Jie Wang
Affiliation:(1) Division of Cardiovascular Diseases, Cardiovascular Research Institute, University of Kansas Medical Center, 3901 Rainbow Blvd, Rm. 1001 Eaton, MS 3006, Kansas City, KS 66160, USA;(2) Division of Cardiovascular Medicine, University of Kentucky, Lexington, KY 40536, USA;(3) Institute of Molecular Cardiology, University of Louisville, Louisville, KY 40292, USA;
Abstract:Heart failure (HF) is a severe heart disease. The use of autologous bone marrow stem cells (BMCs) mobilization in the treatment of HF has been a hot topic to research both in Western medicine and Chinese medicine (CM). There are many clinical trials and experiments on study of BMCs mobilization for HF therapy, including integrative medicine. The effect of BMCs mobilization is favorable for cardiac repair, while some advantages of CM support the advanced study of its application in BMCs mobilization to treat HF. In addition, with mechanisms of autologous BMCs mobilization for the treatment of HF that will be revealed in the future, especially stem cells niches, integrative medicine would play an important role in this clinical thought of therapy model gradually. Simultaneously, CM should adapt the new approaches of stem cells progresses on HF treatment as holding characteristics of itself.
Keywords:autologous bone marrow stem cells mobilization   heart failure   Chinese medicine   cardiac repair
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