子痫前期孕妇外周血及脐血中CD4+CD25+T细胞比例的变化 |
| |
引用本文: | 王轶英. 子痫前期孕妇外周血及脐血中CD4+CD25+T细胞比例的变化[J]. 中国优生与遗传杂志, 2008, 16(8): 20-21 |
| |
作者姓名: | 王轶英 |
| |
作者单位: | 河南省人民医院妇产科,郑州450003 |
| |
摘 要: | 目的 研究子痫前期孕妇外周血及脐血中CD4+CD25+T细胞的比例变化,探讨CD4+CD25+T细胞在妊娠免疫中的作用。方法 应用流式细胞技术检测孕妇外周血及脐血中CD4+CD25+T细胞的比例变化。结果 子痫前期孕妇外周血及脐血中CD4+CD25+T细胞比例较低,低于同孕期的正常妊娠组P〈0.05)。结论 CD4+CD25+T细胞在妊娠期高血压疾病的发生发展中发挥一定作用。
|
关 键 词: | 母胎耐受 调节性 T细胞 |
The shift of the percentage of CD4+CD25+T cells at preeclampsia |
| |
Affiliation: | WANG Yi - ying. ( Department of Obstetrics and Gynecology, Henan Provincial People's Hospital, Henan 450003, China) |
| |
Abstract: | Objective: To investigate the shift of the percentage of CD4 + CD25 + T cells at preeclampsia in peripheral blood or cord blood of pregnant female. To explore the role of CD4 + CD25 + T cells in abnormal pregnancy. Methods : To measure the shift percentage of CD4 + CD25 + T cells in the peripheral blood or cord blood of pregnant women by fluorescence - activated cell sorter (FACS) lysis method. Results : The percentage of CD4 + CD25 + T cells of peripheral blood or cord blood was lower than that of normal pregnant women ( P 〈 0. 05 ). Conclusion : CD4 + CD25 + T cells may play important roles on the abnormal pregnancy - preeclampsia and feto - maternal tolerance. |
| |
Keywords: | Feto - maternal tolerance Regulatory T cells |
本文献已被 维普 万方数据 等数据库收录! |