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The role of the T3 molecular complex in antigen recognition and subsequent activation events
Affiliation:1. Department of Pharmacognosy and Phytochemistry, B. V. Patel Pharmaceutical Education and Research Development (PERD) Centre, Ahmedabad, Gujarat, India;2. Department of Life science, School of Science, Gujarat University, Ahmedabad, Gujarat, India;3. Department of Pharmaceutical Chemistry, L. M. College of Pharmacy, Navrangpura, Ahmedabad, Gujarat, India;4. School of Chemical Sciences, Central University of Gujarat, Gandhinagar, Gujarat, India;5. Centre for Applied Chemistry, Central University of Gujarat, Gandhinagar, Gujarat, India;1. Catalan Institute for Water Research (ICRA), Girona, Spain;2. Universitat de Girona, Girona, Spain;3. Norwegian Institute for Water Research (NIVA), Oslo, Norway;4. Department of Lake Research, Helmholtz Centre for Environmental Research, Magdeburg, Germany;5. Dundalk Institute of Technology, Dundalk, Co. Louth, Ireland;6. Grupo de Meteorología. Dpto. de Matemática Aplicada y Ciencias de la Computación, Universidad de Cantabria, Santander, Spain;7. Foras na Mara - Marine Institute, Furnace, Newport, Co. Mayo, Ireland
Abstract:Monoclonal antibodies raised against human T lymphocytes have identified several cell surface structures that are intimately involved in T-cell function. Perhaps the most familiar is the structure labelled T3. First identified as an antigen five years ago, it is now known to be a complex of at least three molecular species that is found on all T lymphocytes. There seems little doubt that T3 is closely associated with the antigen receptor on these cells, but how? A new (and different) answer is proposed in each of the following articles.
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