Comparison of Outcomes of Mild and Severe Community- and Hospital-Acquired Acute Kidney Injury |
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Authors: | Kristianne Rachel Palanca Medina Jong Cheol Jeong Ji Won Ryu Eunjeong Kang Ho Jun Chin Ki Young Na Dong-Wan Chae Sejoong Kim |
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Affiliation: | 1.Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.;2.Department of Internal Medicine, Ewha Womans University School of Medicine, Seoul, Korea. |
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Abstract: | PurposeAcute kidney injury (AKI) has shown an increasingly common occurrence among hospitalized patients worldwide. We determined the incidence and compared the short- and long-term outcomes of all stages of community-acquired AKI (CA-AKI) and hospital-acquired AKI (HA-AKI), and identified predictors for such outcomes.Materials and MethodsThis observational, single-center, retrospective study identified patients admitted between January 2013 and December 2013 who developed CA-AKI or HA-AKI. Short- and long-term patient and renal outcomes were analyzed.ResultsAKI incidence was 14.3% (1882, CA-AKI 4.8% and HA-AKI 9.5%). The highest 30-day and 1-year mortality were recorded in the CA-AKI group. Thirty-day mortality rate was 11.4% in CA-AKI group and 5.7% in HA-AKI group (p<0.001). One-year mortality rates were 20.1% and 13.3%, respectively (p<0.001). More CA-AKI patients developed kidney failure with replacement therapy within 1 year (27, 4.3% vs. 18, 1.4% respectively, p<0.001).ConclusionIn conclusion, patients with CA-AKI had worse short- and long-term outcomes compared to HA-AKI patients. AKI severity and discharge serum creatinine were significant independent predictors of 30-day and 1-year mortality. |
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Keywords: | Acute kidney injury community-acquired hospital-acquired mortality outcomes |
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