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Experimental Observation on Osteogenetic Effects of Allogenic Decalcified Bone Matrix
引用本文:陈受谦,刘长江,黄旭东,林贵德,高奉浔,张大春,钱昶文,黄明德,李德琼,张序芳,李叶君,吴志峰,杨志发. Experimental Observation on Osteogenetic Effects of Allogenic Decalcified Bone Matrix[J]. 中国人民解放军军医大学学报, 1986, 0(1)
作者姓名:陈受谦  刘长江  黄旭东  林贵德  高奉浔  张大春  钱昶文  黄明德  李德琼  张序芳  李叶君  吴志峰  杨志发
作者单位:Department of Orthopedics Third Teaching Hospital,Third Military Medical College,Chongqing.,Department of Orthopedics,Third Teaching Hospital,Third Military Medical College,Chongqing.,Department of Orthopedics,Third Teaching Hospital,Third Military Medical College,Chongqing.,Department of Orthopedics,Third Teaching Hospital,Third Military Medical College,Chongqing.,Department of Orthopedics,Third Teaching Hospital,Third Military Medical College,Chongqing.,Research Institute of Surgery,Third Military Medical College,Chongqing,Research Institute of Surgery,Third Military Medical College,Chongqing,Research Institute of Surgery,Third Military Medical College,Chongqing,Research Institute of Surgery,Third Military Medical College,Chongqing,Research Institute of Surgery,Third Military Medical College,Chongqing,Research Institute of Surgery,Third Military Medical College,Chongqing,Research Institute of Surgery,Third Military Medical College,Chongqing,Research Institute of Surgery,Third Military Medical College,Chongqing
摘    要:This experiment was designed to evaluate the osteogenetic effects ofdifferent forms of allogenic decalcified bone matrix.39 rabbits were em-ployed and a bony defect of 1cm in length was made on the shaft of theulnas of the animals.They were divided into 4 groups.In the first group,the bony defects were filled with allogenic decalcified bone powder,in thesecond group,with decalcified bone blocks,in the third group,with unde-calcified bone blocks,and in the fourth group,nothing was filled into thebony defects.Roentgenological and histological studies were made regularly.It was found that after 8-10weeks,70-80% of the bony defects filledwith DBM showed firm union between the host bone and the graftedmaterial and no difference of the osteogenecity could be found between thetwo kinds of DBM,incomplete union occurred in the third group,andnonunion was seen in the fourth group.It is suggested that allogenic decalcified bone powder be used as a graftma-terial to fill up bony defects or cavities because it is easily preparedand used,has good plasticity,and can be stored in room temperature.


Experimental Observation on Osteogenetic Effects of Allogenic Decalcified Bone Matrix
Chen Shouqian Liu Changjiang Huang Xudong Lin Guide Gao Fengxun. Experimental Observation on Osteogenetic Effects of Allogenic Decalcified Bone Matrix[J]. Journal of Medical Colleges of PLA(China), 1986, 0(1)
Authors:Chen Shouqian Liu Changjiang Huang Xudong Lin Guide Gao Fengxun
Affiliation:Chen Shouqian Liu Changjiang Huang Xudong Lin Guide Gao Fengxun Department of Orthopedics,Third Teaching Hospital,Third Military Medical College,Chongqing.Zhang Dachun Qian Changwen Huang Mingde Li Deqiong Zhang Xufang Li Yejun Wu Zhifeng Yang Zhifa Research Institute of Surgery,Third Military Medical College,Chongqing
Abstract:This experiment was designed to evaluate the osteogenetic effects of different forms of allogenic decalcified bone matrix.39 rabbits were em- ployed and a bony defect of 1cm in length was made on the shaft of the ulnas of the animals.They were divided into 4 groups.In the first group, the bony defects were filled with allogenic decalcified bone powder,in the second group,with decalcified bone blocks,in the third group,with unde- calcified bone blocks,and in the fourth group,nothing was filled into the bony defects.Roentgenological and histological studies were made regularly. It was found that after 8-10weeks,70-80% of the bony defects filled with DBM showed firm union between the host bone and the grafted material and no difference of the osteogenecity could be found between the two kinds of DBM,incomplete union occurred in the third group,and nonunion was seen in the fourth group. It is suggested that allogenic decalcified bone powder be used as a graft ma-terial to fill up bony defects or cavities because it is easily prepared and used,has good plasticity,and can be stored in room temperature.
Keywords:transplantation  allogenic  decalcified bone matrix  osteogenetic effect  rabbits
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